Melanotan II
MT-2, also known as Melanotan II, is a synthetic peptide belonging to the melanocortin receptor agonist class. It is structurally derived from alpha-melanocyte-stimulating hormone and is designed to interact with melanocortin receptors, including MC1 and MC4 pathways. It is studied for its role in modulating pigmentation and central melanocortin signaling processes. Commonly utilized in research settings to investigate peptide-mediated signaling mechanisms related to melanocortin receptor activity. Supplied by Peptico for research-use only.
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Format
Lyophilized powder
Approved Exclusively For
Laboratory and Analytical Research
Handling
Utilize appropriate sterile technique and controlled environments during preparation.
Short-Term Storage - Lyophilized Powder Form Only
- For maximum potency, lyophilized materials may generally be stored between 2°C and 8°C (36°F to 46°F) for up to 4 weeks when maintained in their original, sealed lyophilized form.
- Maintain a cool and dry environment.
- Protect from moisture and light.
- Minimize exposure to humidity and temperature fluctuations.
Long-Term Storage - Lyophilized Powder Form Only
- For maximum potency and long-term preservation, lyophilized materials may generally be stored between -20°C and -80°C (-4°F to -112°F) for up to 1 year when preserved in their original, sealed lyophilized form.
- Maintain a cool and dry environment.
- Protect from moisture and light.
- Minimize exposure to humidity and temperature fluctuations.
Important Note:
Storage guidelines apply only to lyophilized material in its original, sealed, and untampered vial.
COA History
All shipped products include a unique batch number printed on the vial label. This batch number corresponds to a third-party Certificate of Analysis tested by an ISO/IEC 17025 accredited laboratory.
The COA attached at the top of this page, along with the COA marked “Current” below, represents the active production batch currently being shipped. This same batch number will appear on the label of your vial.
For previous purchases, please refer to COAs marked “Historical” and match the batch number on your vial to the batch number listed on the corresponding COA.
For a complete record of testing documentation across all products and batches, please visit our COA Vault, which includes both current and historical COAs.
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Molecular Profile
What is Melanotan II?
Scientific compound data sourced from PubChem.
Chemical Structure
PubChem CID 92432
Type
Peptide compound
PubChem CID
92432
CAS Number
121062-08-6
Molecular Formula
C50H69N15O9
Molecular Weight
1024.20 g/mol
IUPAC Name
(3S,6S,9R,12S,15S,23S)-15-[[(2S)-2-acetamidohexanoyl]amino]-9-benzyl-6-[3-(diaminomethylideneamino)propyl]-12-(1H-imidazol-5-ylmethyl)-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,17-hexaoxo-1,4,7,10,13,18-hexazacyclotricosane-23-carboxamide
InChIKey
JDKLPDJLXHXHNV-MFVUMRCOSA-N
Research
Sources & References
API results related to Melanotan II.
PubChem
Compound data
Melanotan II compound record
CID: 92432
Formula: C50H69N15O9 • Molecular weight: 1024.2
View source
PubMed
Scientific paper
Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report.
Life (Basel, Switzerland)
Publication date: 2026 Feb 3
View source
PubMed
Scientific paper
Melanotan II nasal spray: a possible risk factor for oral mucosal malignant melanoma?
International journal of oral and maxillofacial surgery
Publication date: 2025 Sep
View source
PubMed
Scientific paper
Antidepressant-like and antistress effects of the ACTH(4-10) synthetic analogs Semax and Melanotan II on male rats in a model of chronic unpredictable stress.
European journal of pharmacology
Publication date: 2024 Dec 5
View source
PubMed
Scientific paper
Barbie drug identification: Not a child's play.
Journal of forensic sciences
Publication date: 2024 Nov
View source
PubMed
Scientific paper
Recommended Tool Compounds for the Melanocortin Receptor (MCR) G Protein-Coupled Receptors (GPCRs).
ACS pharmacology & translational science
Publication date: 2024 Sep 13
View source⚠️ IMPORTANT RESEARCH NOTICE
This product is NOT for human consumption.
Supplied strictly for laboratory and analytical research use only, it is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for clinical, veterinary, or therapeutic applications.
All information provided, including referenced research and data, is for educational and scientific context only and should NOT be interpreted as medical guidance.
By purchasing, you confirm that you are a qualified individual or entity operating in accordance with applicable local, state, and federal regulations. All responsibility for handling, use, and compliance rests solely with the purchaser.
