Retatrutide
Retatrutide is a synthetic tri-agonist peptide engineered to interact with GLP-1, GIP, and glucagon receptor signaling pathways. Through this tri-agonist mechanism, it is utilized in research settings to study metabolic signaling processes, receptor signaling pathways, and peptide-mediated cellular communication. Supplied by Peptico for research-use only.
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Format
Lyophilized powder
Approved Exclusively For
Laboratory and Analytical Research
Handling
Utilize appropriate sterile technique and controlled environments during preparation.
Short-Term Storage - Lyophilized Powder Form Only
- For maximum potency, lyophilized materials may generally be stored between 2°C and 8°C (36°F to 46°F) for up to 4 weeks when maintained in their original, sealed lyophilized form.
- Maintain a cool and dry environment.
- Protect from moisture and light.
- Minimize exposure to humidity and temperature fluctuations.
Long-Term Storage - Lyophilized Powder Form Only
- For maximum potency and long-term preservation, lyophilized materials may generally be stored between -20°C and -80°C (-4°F to -112°F) for up to 1 year when preserved in their original, sealed lyophilized form.
- Maintain a cool and dry environment.
- Protect from moisture and light.
- Minimize exposure to humidity and temperature fluctuations.
Important Note:
Storage guidelines apply only to lyophilized material in its original, sealed, and untampered vial.
COA History
All shipped products include a unique batch number printed on the vial label. This batch number corresponds to a third-party Certificate of Analysis tested by an ISO/IEC 17025 accredited laboratory.
The COA attached at the top of this page, along with the COA marked “Current” below, represents the active production batch currently being shipped. This same batch number will appear on the label of your vial.
For previous purchases, please refer to COAs marked “Historical” and match the batch number on your vial to the batch number listed on the corresponding COA.
For a complete record of testing documentation across all products and batches, please visit our COA Vault, which includes both current and historical COAs.
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Molecular Profile
What is Retatrutide?
No PubChem molecular profile was found for this product.
Research
Sources & References
API results related to Retatrutide.
PubMed
Scientific paper
Benefits and Harms of Pharmacologic Treatments in Adults With Overweight or Obesity: A Living Systematic Review and Network Meta-analysis for the American College of Physicians.
Annals of internal medicine
Publication date: 2026 Jun 16
View source
PubMed
Scientific paper
Efficacy and safety of retatrutide, a GIP, GLP-1, and glucagon receptor agonist, in people with type 2 diabetes and inadequate glycaemic control with diet and exercise (TRANSCEND-T2D-1): a double-blind, randomised, phase 3 trial.
Lancet (London, England)
Publication date: 2026 Jun 13
View source
PubMed
Scientific paper
GLP-1 Agonists in Adolescent Obesity: A Narrative Review of Single, Dual, and Triple Agonists.
Diabetes, metabolic syndrome and obesity : targets and therapy
Publication date: 2026
View source
PubMed
Scientific paper
A Hydrophobic Tag-Assisted Liquid-Phase Strategy for the Synthesis of Retatrutide.
Organic letters
Publication date: 2026 Jun 12
View source
PubMed
Scientific paper
Retatrutide: Triple acting jab for type 2 diabetes lowers blood sugar and boosts weight loss, trial reports.
BMJ (Clinical research ed.)
Publication date: 2026 Jun 9
View source
PubMed
Scientific paper
Synergistic Intervention for Obesity: Integrating Central Appetite Regulation and Peripheral Energy Expenditure.
Current obesity reports
Publication date: 2026 Jun 6
View source⚠️ IMPORTANT RESEARCH NOTICE
This product is NOT for human consumption.
Supplied strictly for laboratory and analytical research use only, it is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for clinical, veterinary, or therapeutic applications.
All information provided, including referenced research and data, is for educational and scientific context only and should NOT be interpreted as medical guidance.
By purchasing, you confirm that you are a qualified individual or entity operating in accordance with applicable local, state, and federal regulations. All responsibility for handling, use, and compliance rests solely with the purchaser.
