IGF-1 LR3
IGF-1 LR3 is a modified analog of insulin-like growth factor-1 (IGF-1) engineered with an extended amino acid sequence and reduced affinity for IGF-binding proteins. It is commonly utilized in research settings to study IGF-1 receptor signaling, cellular growth pathways, and protein synthesis. Supplied by Peptico for research-use only.
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- For maximum potency, lyophilized materials may generally be stored between 2°C and 8°C (36°F to 46°F) for up to 4 weeks when maintained in their original, sealed lyophilized form.
- Maintain a cool and dry environment.
- Protect from moisture and light.
- Minimize exposure to humidity and temperature fluctuations.
- For maximum potency and long-term preservation, lyophilized materials may generally be stored between -20°C and -80°C (-4°F to -112°F) for up to 1 year when preserved in their original, sealed lyophilized form.
- Maintain a cool and dry environment.
- Protect from moisture and light.
- Minimize exposure to humidity and temperature fluctuations.
Important Note:
Storage guidelines apply only to lyophilized material in its original, sealed, and untampered vial.
COA History
All shipped products include a unique batch number printed on the vial label. This batch number corresponds to a third-party Certificate of Analysis tested by an ISO/IEC 17025 accredited laboratory.
The COA attached at the top of this page, along with the COA marked “Current” below, represents the active production batch currently being shipped. This same batch number will appear on the label of your vial.
For previous purchases, please refer to COAs marked “Historical” and match the batch number on your vial to the batch number listed on the corresponding COA.
For a complete record of testing documentation across all products and batches, please visit our COA Vault, which includes both current and historical COAs.
Molecular Profile
What is IGF-1 LR3?
Research
Sources & References
API results related to IGF-1 LR3.
The emerging landscape of performance-enhancing peptides modulating GH-IGF1 axis: bridging the gap between clinical evidence and patient self-administration.
Frontiers in endocrinology
Dominikowski A, Rękoś Z, Olejarz M et al. • 2026
Publication date: 2026
View sourceRevolutionary decellularized Alstroemeria stem-based nerve conduit integrated with GelMA and controlled IGF-1 LR3 release for enhanced rat sciatic nerve regeneration.
International journal of biological macromolecules
Yavuz E, Sağır MS, Ercan A et al. • 2025
Publication date: 2025 Nov
View sourceIGF-1 LR3 does not promote growth in late-gestation growth-restricted fetal sheep.
American journal of physiology. Endocrinology and metabolism
White A, Stremming J, Wesolowski SR et al. • 2025
Publication date: 2025 Jan 1
View sourceIntranasal long R3 insulin-like growth factor-1 treatment promotes amyloid plaque remodeling in cerebral cortex but fails to preserve cognitive function in male 5XFAD mice.
Journal of Alzheimer's disease : JAD
Engel MG, Narayan S, Cui MH et al. • 2025
Publication date: 2025 Jan
View sourceRecombinant expression of IGF-1 and LR3 IGF-1 fused with xylanase in Pichia pastoris.
Applied microbiology and biotechnology
Lu Z, Liu N, Huang H et al. • 2023
Publication date: 2023 Jul
View sourceAttenuated glucose-stimulated insulin secretion during an acute IGF-1 LR3 infusion into fetal sheep does not persist in isolated islets.
Journal of developmental origins of health and disease
White A, Stremming J, Brown LD et al. • 2023
Publication date: 2023 Jun
View source⚠️ IMPORTANT RESEARCH NOTICE
This product is NOT for human consumption.
Supplied strictly for laboratory and analytical research use only, it is not intended to diagnose, treat, cure, or prevent any disease, and must not be used for clinical, veterinary, or therapeutic applications.
All information provided, including referenced research and data, is for educational and scientific context only and should NOT be interpreted as medical guidance.
By purchasing, you confirm that you are a qualified individual or entity operating in accordance with applicable local, state, and federal regulations. All responsibility for handling, use, and compliance rests solely with the purchaser.


